Through recent research advances we are increasingly able to understand and address immune-mediated diseases. Biotechnology is yielding success in areas with a strong immunologic component, such as allergic asthma, rheumatoid arthritis, inflammatory bowel disease, psoriasis and multiple sclerosis. Nevertheless, the burden of immune-mediated diseases is still enormous, with direct and indirect costs associated with such conditions believed to exceed $100 billion in the USA alone.

Expert Review of Clinical Immunology (ISSN 1744-666X) provides expert analysis and commentary regarding the performance of new therapeutic and diagnostic modalities in clinical immunology. Members of the International Editorial Advisory Panel of Expert Review of Clinical Immunology are the forefront of their area of expertise. This panel works with our dedicated editorial team to identify the most important and topical review themes and the corresponding expert(s) most appropriate to provide commentary and analysis. All articles are subject to rigorous peer-review, and the finished reviews provide an essential contribution to decision-making in clinical immunology.

Articles focus on the following key areas:
• Therapeutic overviews of specific immunologic disorders highlighting optimal therapy and prospects for new medicines
• Performance and benefits of newly approved therapeutic agents
• New diagnostic approaches
• Screening and patient stratification
• Pharmacoeconomic studies
• New therapeutic indications for existing therapies
• Adverse effects, occurrence and reduction
• Prospects for medicines in late-stage trials approaching regulatory approval
• Novel treatment strategies
• Epidemiological studies
• Commentary and comparison of treatment guidelines

Topics include infection and immunity, inflammation, host defense mechanisms, congenital and acquired immunodeficiencies, anaphylaxis and allergy, systemic immune diseases, organ-specific inflammatory diseases, transplantation immunology, endocrinology and diabetes, cancer immunology, neuroimmunology and hematological diseases.

The Expert Review format is unique. Each review provides a complete overview of current thinking in a key area of clinical immunology. Comprehensive coverage is augmented by:

Expert Opinion - a personal view on the most effective or promising strategies and a perspective on future prospects over the next 5 years
Article Highlights - an executive summary cutting to the author's most critical points

Many medical centers are now focusing resources specifically on immunologic disorders, and the primary literature associated with new and emerging approaches to therapy, diagnosis and outcomes research in immune-mediated diseases is burgeoning. It is no longer feasible for an individual to track and analyze all of these advances. Expert Review of Clinical Immunology provides a centralized resource of commentary and debate for this community to inform clinical and economic decision-making in healthcare delivery.

We welcome suggestions or recommendations for Guest Editorials, Meeting Reports, Reviews or Drug Profiles for publication in Expert Review of Clinical Immunology . In the first instance, please contact the Commissioning Editor.