One of the premier peer-reviewed clinical journals in general and internal medicine, Mayo Clinic Proceedings is among the most widely read and highly cited scientific publications for physicians, with a circulation of approximately 127,000. While the Proceedings is sponsored by Mayo Clinic, it welcomes submissions from authors worldwide, publishing articles that focus on clinical medicine and support the professional and educational needs of its readers.

Continuously published since 1926, the Mayo Clinic Proceedings' content includes Nobel-prize-winning research. The Proceedings has an impact factor of 7.091, ranking it #12 out of 160 journals in the Medicine, General and Internal category, placing it among the best 8%. The Proceedings has experienced numerical increases in its Impact Factor for 17 of the past 21 years.

Mayo Clinic Proceedings welcomes manuscripts that focus on clinical and laboratory medicine, health care policy and economics, medical education and ethics, and related topics:
Each monthly issue presents approximately 15 individual articles and features, consisting of original research, reviews, clinical content, editorials, commentaries, brief reports, special articles, and other short items.
Among unique articles are Concise Review for Clinicians, Residents' Clinics, and specially commissioned Thematic Reviews.
My Treatment Approach articles present expert opinion on difficult clinical situations.
Consensus Recommendations provide answers to questions not resolved in other published guidelines.
The journal carries articles that offer free CME credit from Mayo Clinic.
The Proceedings also offers substantial online-only content as well as supplemental material and videos directly related to individual articles.

Original articles
Review articles
concise reviews
understanding disease
special aticles
commentary
perspectives
brief report
editorials
letter to the editor
medical images